.Pharmacolibrary.Drugs.V_Various.V03A_AllOtherTherapeuticProducts.V03AF10_SodiumLevofolinate.SodiumLevofolinate .Pharmacolibrary.Drugs.V_Various.V03A_AllOtherTherapeuticProducts.V03AF10_SodiumLevofolinate.SodiumLevofolinate| name: | SodiumLevofolinate | |
| ATC code: | V03AF10 | |
| route: | intravenous | |
| compartments: | 1 | |
| dosage: | 50 | mg |
| volume of distribution: | 10 | L |
| clearance: | 180 | mL/min |
| other parameters in model implementation | ||
Sodium levofolinate, also known as levoleucovorin, is the active (S)-enantiomer of folinic acid. It is used as a chemoprotective agent to reduce the toxicity of methotrexate therapy and to enhance the efficacy of fluoropyrimidine-based chemotherapy. Approved for medical use, it is administered parenterally, often intravenously, as a rescue agent in cancer chemotherapy regimens.
Pharmacokinetic estimate for adults (no published human PK model located, see notes).