modelPeriodicDose_Enteral
periodic enteral (oral) dose model
Extends from PeriodicDose (periodic dose model).
Information
PeriodicDose_Enteral
Periodic dose source for enteral administration (oral, rectal, sublingual): same pulse schedule as PeriodicDose, with the route redeclared to FirstOrderAbsorption (absorption lag
Tlag then first-order uptake ka from a depot compartment).Tlag - time lag between administration and absorption (default 10 min)
ka - first order absorption rate from the GI tract
Parameters
| Type | Name | Default | Description |
|---|---|---|---|
| Modelica.Units.SI.Time | firstAdminTime (from PartialPeriodicDoseSource) | 0 | time of first dose |
| Modelica.Units.SI.Time | adminPeriod (from PartialPeriodicDoseSource) | 8*3600 | time period between doses |
| Pharmacolibrary.Types.Mass | adminMass (from PartialPeriodicDoseSource) | 0.001 | drug dose mass |
| Integer | doseCount (from PartialPeriodicDoseSource) | -1 | number of doses, -1 = unlimited |
| Modelica.Units.SI.Time | adminDuration (from PartialPeriodicDoseSource) | 1 | administration duration |
| Real | F (from PartialPeriodicDoseSource) | 1 | bioavailability [0-1] |
| Pharmacolibrary.Types.TransferRate | ka | 0.0016666666666667 | first order absorption rate |
| Modelica.Units.SI.Time | Tlag | 600 | time delay between administration and absorption (default 10 min) |
Connectors
| Type | Name | Default | Description |
|---|---|---|---|
| ConcentrationPort_b | cport (from PartialDrugSource) |
Components
| Type | Name | Default | Description |
|---|---|---|---|
| Pharmacolibrary.Types.Mass | TotalCumulativeMass (from PartialDrugSource) | Total dose adminitrated by this source | |
| Absorption.DirectAbsorption | route (from PeriodicDose) |